product name：Human Pancreatic Stellate Cells(人胰腺星狀細胞)；

cat no：ABC-TC3746；

Size/Quantity：1 vial；

Biosafety Level：1；

Shipping Info：Dry Ice；

Storage：Liquid Nitrogen；

Description：Pancreatic stellate cells (PSCs,人胰腺星狀細胞) comprise 4-7% of parenchymal cells in the pancreas. They play an important role in desmoplastic reaction associated with pancreas diseases. In its quiescence state, human pancreatic stellate cells mainly serve as retinoids (vitamin A and its analogous), storing cells and secreting metalloproteinase that responsible for ECM turnover. Damage to pancreatic tissue, inflammation and carcinogenesis can activate pancreas stellate cells into myofibroblast-like phenotype and increase expression of α-smooth muscle actin (α-SMA). Accumulating evidence have suggested that pancreatic stellate cells play an important role in desmoplastic reaction that can lead to chronic pancreatitis such as malnutrition and diabetes. Their facilitative role during pancreatic cancer metabolism and metastasis has also raised great interest in cancer pathophysiology.；

Quality Control：All cells test negative for mycoplasma, bacteria, yeast, and fungi；

Application：For research use only.

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